1915-S Buffalo Nickel. MS-65+ (PCGS). CAC.Sharply to fully struck throughout the design, this exceptional San Francisco Mint Buffalo nickel also has smooth satin luster on both sides and warm, golden-gray toning. It will be just right for a high grade Buffalo nickel set. From a relatively small mintage of 1,505,000 pieces, the 1915-S is conditionally challenging and typically found in the lowest circulated grades.